Phylogeny Analysis

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Genetic ancestry of a KoRef donor

Linage of Y, mtDNA, and autosomes

To identify the paternal and maternal linage of a Korean genome, Y, mtDNA, and autosomes were traced separately. When compared with Y Chromosome Consortium haplogroup markers (Karafet et al, 2008), the KoRef donor Y chromosome had variations which are known as the markers of a sub-haplogroup "O2b"(Fig X). The O2b sub-haplogroup is of high frequency in the Korean and Japanese populations, and is a sub group of O haplogroup who probably originated in East Asia and later migrated into the South Pacific. The mtDNA haplotype suggested XXXXX (Fig. X). The autosomal linage was similar(or different, or similar to Y chromosome, or only similar to mtDNA) to XXX and a Korean donor was located between CHB and JPT (Fig. X).

Discussion

 

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The KoRef donor Y chromosome haplotype suggests descent from several North/East Asian groups given the Y chromosome ethno-geographic markers. The haplogroup membership is R1b6 with includes individuals from the United Kingdom, Germany, Russia, and the United States, which is consistent with the self-reported family tree provided by the HuRef donor. The thick red line denotes the markers needed to trace the haplotype from the mapping of the chromosome Y markers to the HuRef genome. Data and figure from the Y Chromosome Consortium;

  

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Fig. 1. Y chromosomal haplotype linage

 

 Fig. 2. Mitochondiral linage

mitochondrial_linage

Fig. 3. Autosomal linage

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