Cho, Yun Sung


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Education and Training

2015-2017                                 Ph.D. in Biomedical Engineering

UNIST (Ulsan National Institute of Science & Technology), Ulsan, Korea


2009-2011                                  M.S. in Bioinformatics

Soongsil University, Seoul, Korea


2003-2009                                  B.S. in Bioinformatics

Soongsil University, Seoul, Korea


Professional Experiences

2011.11-2014.06                       Senior Researcher

Personal Genomics Institute, Genome Research Foundation, Cheongju, Korea


2014.07-2017.06                        Vice-director

Personal Genomics Institute, Genome Research Foundation, Cheongju, Korea


2014.07-2017.06                        Vice-director of TGI

The Genomics Institute of UNIST (Ulsan National Institute of Science & Technology), Ulsan, Korea


Work experiences

- Bioinformatics: Reference genome, Genome project, Comparative genomics, Cancer genome analysis

- Chemoinformatics: Protein modeling, Docking, Virtual screening, Chemical compound notation



- (co-corresponding author) Myotis rufoniger genome sequence and analyses: M. rufoniger's genomic feature and the decreasing effective population size of Myotis bats.

Bhak Y, Jeon Y, Jeon S, Chung O, Jho S, Jun J, Kim HM, Cho Y, Yoon C, Lee S, Kang JH, Lim JD, An J, Cho YS, Ryu DY, Bhak J. PLoS One 12, e0180418 (2017).


- (co-author) Genome-wide data from two early Neolithic East Asian individuals dating to 7700 years ago.

Siska V, Jones ER, Jeon S, Bhak Y, Kim HM, Cho YS, Kim H, Lee K, Veselovskaya E, Balueva T, Gallego-Llorente M, Hofreiter M, Bradley DG, Eriksson A, Pinhasi R, Bhak J, Manica A. Sci. Adv. 3, e1601877 (2017).


- (co-author) Perspectives provided by leopard and other cat genomes: how diet determined the evolutionary history of carnivores, omnivores, and herbivores.

Kim S, Cho YS, Bhak J, O'Brian SJ, Yeo JH. BMB Rep. 50, 3-4 (2017).


- (co-author) Analysis of the FGF gene family provides insights into aquatic adaptation in cetaceans.

Nam K, Lee KW, Chung O, Yim HS, Cha SS, Lee SW, Jun J, Cho YS, Bhak J, Magalhães JP, Lee JH, Jeong JY. SciRep. 7, 40233 (2017).


- (co-first author) An ethnically relevant consensus Korean reference genome is a step towards personal reference genomes.

Cho YS, Kim H, Kim HM, Jho S, Jun J, Lee YJ, Chae KS, Kim CG, Kim S, Eriksson A, Edwards JS, Lee S, Kim BC, Manica A, Oh TK, Church GM, Bhak J. Nat. Commun. 7, 13637 (2016).


- (co-first author) Comparison of carnivore, omnivore, and herbivore mammalian genomes with a new leopard assembly.

Kim S, Cho YS, Kim HM, Chung O, Kim H, Jho S, Seomun H, Kim J, Bang WY, Kim C, An J, Bae CH, Bhak Y, Jeon S, Yoon H, Kim Y, Jun J, Lee H, Cho S, Uphyrkina O, Kostyria A, Goodrich J, Miquelle D, Roelke M, Lewis J, Yurchenko A, Bankevich A, Cho J, Lee S, Edwards JS, Weber JA, Cook J, Kim S, Lee H, Manica A, Lee I, O'Brien SJ, Bhak J, Yeo JH. Genome Biol. 17, 211 (2016).


- (co-author) The genetics of an early Neolithic pastoralist from the Zagros, Iran.

Gallego-Llorente M, Connell S, Jones ER, Merrett DC, Jeon Y, Eriksson A, Siska V, Gamba C, Meiklejohn C, Beyer R, Jeon S, Cho YS, Hofreiter M, Bhak J, Manica A, Pinhasi R. Sci. Rep. 6, 31 (2016).


- (co-first author) The first whole genome and transcriptome of the Cinereous vulture reveals adaptation in the gastric and immune defense systems and possible convergent evolution between the Old and New World vultures.

Chung O, Jin S, Cho YS, Lim J, Kim H, Jho S, Kim HM, Jun J, Lee H, Chon A, Ko J, Edwards J, Weber JA, Han K, O'Brien SJ, Manica A, Bhak J, Paek WK. Genome Biol. 16, 215 (2015).


 - (co-author) Gene loss in keratinization programs accompanies adaptation of Cetacean skin to aquatic lifestyle.

Oh JW, Chung O, Cho YS, MacGregor GR, Plikus MV. Exp. Dermatol. doi: 10.1111/exd.12756. (2015).


- (co-author) Whole genome sequencing of an ethnic Pathan (Pakhtun) from the north-west of Pakistan.

Ilyas M, Kim JS, Cooper J, Shin YA, Kim HM, Cho YS, Hwang S, Kim H, Moon J, Chung O, Jun J, Rastogi A, Song S, Ko J, Manica A, Rahman Z, Husnain T, Bhak J. BMC Genomics 16:172 (2015).


- (co-author) Molecular adaptation of the CREB-Binding Protein for aquatic living in cetaceans.

Jeong JY, Chung OS, Ko YJ, Lee KW, Cho YS, Bhak J, Yim HS, Lee JH. J. Mar. Biosci. Biotechnol. 6, 102-109 (2014).


- (co-first author) Whole genome sequence and analysis of the Marwari horse breed and its genetic origin.

Jun J, Cho YS, Hu H, Kim HM, Jho S, Gadhvi P, Park KM, Lim J, Paek WK, Han K, Manica A, Edwards JS, Bhak J. BMC Genomics 15(Suppl 9), S4 (2014).


- (co-author) Variation block-based genomics method for crop plants.

Kim YH, Park HM, Hwang TY, Lee SK, Choi MS, Jho S, Hwang S, Kim HM, Lee D, Kim BC, Hong CP, Cho YS, Kim H, Jeong KH, Seo MJ, Yun HT, Kim SL, Kwon YU, Kim WH, Chun HK, Lim SJ, Shin YA, Choi IY, Kim YS, Yoon HS, Lee SH, Lee S. BMC Genomics 15, 477 (2014).


- (co-first author) Genomic profile analysis of diffuse-type gastric cancers.

Lee YS, Cho YS, Lee GK, Lee S, Kim YW, Jho S, Kim HM, Hong SH, Hwang JA, Kim SY, Hong D, Choi IJ, Kim BC, Kim BC, Kim CH, Choi H, Kim Y, Kim KW, Kong G, Kim HL, Bhak J, Lee SH, Lee JS. Genome Biol. 15, R55 (2014).


- (co-first author) Minke whale genome and aquatic adaptation in cetaceans.

Yim HS, Cho YS, Guang X, Kang SG, Jeong JY, Cha SS, Oh HM, Lee JH, Yang EC, Kwon KK, Kim YJ, Kim TW, Kim W, Jeon JH, Kim SJ, Choi DH, Jho S, Kim HM, Ko J, Kim H, Shin YA, Jung HJ, Zheng Y, Wang Z, Chen Y, Chen M, Jiang A, Li E, Zhang S, Hou H, Kim TH, Yu L, Liu S, Ahn K, Cooper J, Park SG, Hong CP, Jin W, Kim HS, Park C, Lee K, Chun S, Morin PA, O'Brien SJ, Lee H, Kimura J, Moon DY, Manica A, Edwards J, Kim BC, Kim S, Wang J, Bhak J, Lee HS, Lee JH. Nat. Genet. 46, 88-92 (2014).


(co-first author) Whole genome comparison of donor and cloned dogs.

Kim HM, Cho YS, Kim H, Jho S, Son B, Choi JY, Kim S, Lee BC, Bhak J, Jang G. SciRep. 3, 2998 (2013).


- (co-first author) The tiger genome and comparative analysis with lion and snow leopard genomes.

Cho YS, Hu L, Hou H, Lee H, Xu J, Kwon S, Oh S, Kim HM, Jho S, Kim S, Shin YA, Kim BC, Kim H, Kim CU, Luo SJ, Johnson WE, Koepfli KP, Schmidt-Küntzel A, Turner JA, Marker L, Harper C, Miller SM, Jacobs W, Bertola LD, Kim TH, Lee S, Zhou Q, Jung HJ, Xu X, Gadhvi P, Xu P, Xiong Y, Luo Y, Pan S, Gou C, Chu X, Zhang J, Liu S, He J, Chen Y, Yang L, Yang Y, He J, Liu S, Wang J, Kim CH, Kwak H, Kim JS, Hwang S, Ko J, Kim CB, Kim S, Bayarlkhagva D, Paek WK, Kim SJ, O'Brien SJ, Wang J, Bhak J. NatCommun. 4, 2433 (2013).


- (co-author) The Genetic Basis of White Tigers.

Xu X, Dong GX, Hu XS, Miao L, Zhang XL, Zhang DL, Yang HD, Zhang TY, Zou ZT, Zhang TT, Zhuang Y, Bhak J, Cho YS, Dai WT, Jiang TJ, Xie C, Li R, Luo SJ. Curr. Biol. 23, 1031-1035 (2013).


- (co-author) Twelve Positions in a b-Lactamase That Can Expand Its Substrate Spectrum with a Single Amino Acid Substitution.

Yi H, Cho KH, Cho YS, Kim K, Nierman WC, Kim HS. PLoS One 7, e37585 (2012).


- (first author) yaInChI: Modified InChI string scheme for line notation of chemical structures.

Cho YS, No KT, Cho KH. SAR. QSAR. Environ. Res. 23, 237-255 (2012).



- (Inventor) Apparatus and method for string expression of compound distinguishing isomer, apparatus and method for searching compound using the same (Registration No. 1012369660000, KIPO), 2013

- (Inventor) Novel single nucleotide variation markers specific for white hair phenotype (Registration No. 1014802070000, KIPO), 2014

- (Inventor) Novel single nucleotide variation markers specific for hypoxia adaptation (Registration No. 1014802080000, KIPO), 2014

- (Inventor) Novel glucosylation enzymes isolated from Balaenoptera acutorostrata scammoni genome and methods of preparation thereof (Application No. 1020130065886, KIPO), 2013

- (Inventor) Novel Angiotensin Converting Enzyme 2 isolated from Balaenoptera acutorostrata scammoni genome and methods of preparation thereof (Application No. 1020130065885, KIPO), 2013

- (Inventor) Novel lipases isolated from Balaenoptera acutorostrata scammoni genome and methods of preparation thereof (Application No. 1020130065884, KIPO), 2013

- (Inventor) Method for sequencing of long genomic DNA with high accuracy (Application No. 1020160178332, KIPO), 2016

- (Inventor) Apparatus and Method for Predicting Status Index of Disease (Application No. 1020160158000, KIPO), 2016

- (Inventor) Apparatus and method for assembling genome sequence using multiple contig (Application No. 1020160159981, KIPO), 2016

- (Inventor) Apparatus and method constructing consensus reference genome map (Application No. 1020170006310, KIPO), 2017


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